Canabidiolic acid, also known as CBDA, is a cannabinoid found in fresh hemp. In raw marijuana there is very little CBD for this a lot of CBDA. This is because CBDA is an acidic precursor to cbd and only after exposure to high temperatures or long-term CBDA drying is transformed into cbd. This process is called decarboxylation, which is a type of chemical reaction that removes the carboxyl group.
Recently, it's very loud about CBD which has been popular lately. Both CBD and CBDA combine several common features , among other things, they do not cause intoxication, because they do not interact directly with receptors in our endocannabinoid system – a complex network of cell receptors and chemicals marijuana-like, which restore balance in our body and mind. The result is better well-being and relaxed body. In addition, CBDA and CBD activate serotonin receptors in the body. Serotonin is involved in regulating sleep, mood, anxiety and nausea is a kind of neurotransmitter found in the brain.
Now, let's take a closer look at its potential medicinal effects of this interesting cannabinoid. So far, no human studies have been conducted using CBDA.
However, the following research gives us an insight into its future uses and so CBDA:
- anti-inflammatory effect ( 2008 study published in the journal Drug Metabolism and Disposition, CBDA exerts in vitro anti-inflammatory effects acting as an inhibitor of cyclooxygenase-2 enzyme (COX-2)
- antidepressants and anxiolytics ( CBDA depression studies have reached only preclinical stage, but so far it has been found to cause antidepressants on rats at doses 10-100 times lower than CBD. It is believed that these anxiolytic and mood-enhancing effects are the result of elevated serotonin levels.)
- the effect against nausea and vomiting especially in cases of chemotherapy and in the case of contraceptive nausea, is effective in reducing side effects ( 2013 study published in the British Journal of Pharmacology, it examined CBDA's effect on behaviour caused by nausea in rats and vomiting in the villains. The study found that CBDA has more efficacy than CBD in inhibiting vomiting and nausea in animal models) scientific research
- inhibits the migration of breast cancer cells on petri's pan ( 2012 study published in the journal Toxicology Letters, cbda is capable of inhibiting the migration of highly invasive human breast cancer cells MDA-MB-231 by inhibiting certain enzymes while activating signal routes that stop motility of various cancer cells. While these limited in vitro studies are far from concrete and do not reflect CBDA's action on cancer in humans, this is an interesting indicator of what future human research can show). Research
- as an antiepileptic drug ( GW Pharmaceuticals, they now own a patent on CBDA as a potential antiepileptic drug. As world leaders in the treatment of cannabinoid epilepsy, they found that CBDA has better bioavailability than CBD. They also noted that cbda needed less than CBDA to achieve the therapeutic effect.
Marijuana has been and has been used by humans for thousands of years as a source of food and drugs. Already egyptians 2,900 BC have used hemp to treat glaucoma and inflammation. It can be said that the effectiveness of marijuana has survived the test of time and is still used and prescribed to help treat many different diseases. Cbd in particular, as it offers relief without intoxicating side effects and exhibits, among other things, anti-inflammatory, antipsychotic, anticancer and antioxidant properties, but cbda has also been evaluated in some scientific research studies and found to bring many potential therapeutic benefits.